A new preclinical study finds that a high-salt diet may drive immune-driven vascular aging by damaging endothelial cells, reducing nitric oxide, and stiffening vessels, with senolytic drugs restoring function in mice but human relevance unknown.

High Salt Diet Accelerates Vascular Aging, Study Warns
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High Salt Diet Accelerates Vascular Aging, Study Warns

New preclinical research suggests that a salt-heavy diet does more than raise blood pressure: it may set off an immune-driven chain reaction that ages the cells lining small arteries, cuts nitric oxide production and impairs blood vessel flexibility, while experimental senolytic drugs restored function in mice but human relevance remains unproven. For decades, too much...